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Simparica Trio is a once-monthly chewable tablet that combines flea, tick, heartworm and intestinal worm protection in one dose. It is the first combination product FDA-approved to kill six tick species, including the deer tick that can carry Lyme disease, and it starts killing fleas within 4 hours with full kill by 8 hours. It suits owners who want a single monthly chew instead of separate flea, tick and heartworm products, and it is approved for puppies from 8 weeks old that meet the minimum weight. The liver-flavored chew is built to be taken voluntarily; in a study, 9 out of 10 dogs ate it on their own.
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Lowest price we've seen: $44.63 on Nov 15 at Amazon. Tracked across 2 stores since Nov 15.
Owners and vets describe Simparica Trio as a convenient all-in-one monthly preventive, with most dogs taking the liver chew without fuss. Complaints center on dogs that refuse the taste and on digestive upset in some animals.
| Weight (lb.) | Sarolaner per Tablet (mg | Moxidectin per Tablet (m | Pyrantel per Tablet (mg) | Number of Tablets Admini |
|---|---|---|---|---|
| 2.8 to 5.5 lb. | 3.0 | 0.06 | 12.5 | 1 |
| 5.5 to 11 lb. | 6.0 | 0.12 | 25 | 1 |
| 11-22 lb. | 12 | 0.24 | 50 | 1 |
| 22-44 lb. | 24 | 0.48 | 100 | 1 |
| 44-88 lb. | 48 | 0.96 | 200 | 1 |
| 88-132 lb. | 72 | 1.44 | 300 | 1 |
Simparica Trio is a once-monthly, liver-flavored chewable tablet for dogs. It protects against heartworms, ticks, fleas, flea tapeworms, roundworms and hookworms. This size is for dogs weighing 44.1 to 88 lb.
It starts killing fleas within 4 hours and reaches 100% effectiveness in 8 hours. That kills fleas before they can lay eggs. It is the first combination preventative FDA-approved to kill six types of ticks, including the deer tick that may carry Lyme infections.
The chew can be given with or without food. In a study, 9 out of 10 dogs took it voluntarily. It is approved for puppies as young as eight weeks old that meet the minimum weight for the size.
