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Simparica Trio is a monthly oral chew that combines three drugs in one tablet: sarolaner for fleas and ticks, moxidectin for heartworm and some intestinal worms, and pyrantel for roundworms and hookworms. That three-in-one coverage is its main edge over older single-purpose products, since owners avoid stacking a flea chew, a heartworm pill and a dewormer. The liver-flavored chew is given once a month to dogs from eight weeks old. It suits owners who want one simple monthly routine, though it requires a prescription and does not cover tapeworm.
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Lowest price we've seen: $40.05 on Nov 15 at Tractor Supply Company. Tracked across 3 stores since Nov 15.
Owners generally rate Simparica Trio highly for convenience and broad coverage, and many report their dogs take the chew without fuss. Complaints center on digestive upset in some dogs and on the prescription requirement.
Simparica Trio is a monthly chewable tablet for dogs weighing 88.1 to 132.0 pounds. It combines three active ingredients: sarolaner, moxidectin, and pyrantel. Each tablet is liver flavored.
The tablet is given by mouth once a month. It can be given to puppies eight weeks old and older. The tablet is reddish brown and pentagon shaped with rounded edges.
