Compared across 3 stores. Prices are checked against each store and labelled with when. Store links may earn us a commission. Price via Klarna.
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Simparica Trio is a monthly chewable that combines flea, tick, heartworm and roundworm/hookworm protection in one tablet, so you skip separate preventives. It is given once a month and is sized by your dog's weight. The 6-pack covers six months. At $228.13 at Chewy as of November 7, 2026, it is the best new price among the 3 stores that carry it.
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Lowest price we've seen: $228.13 on Nov 7 at Tractor Supply Co. Tracked across 3 stores since Nov 7.
Owners generally report their dogs take the chew without fuss and that it keeps fleas and ticks off. A minority describe stomach upset, vomiting or refusal in picky dogs.