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Simparica
Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)

Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)

4.9(52 ratings)

Best price now

$25.71at AmazonChecked 1 h ago

88% under what the other stores charge

Compared across 16 stores. Prices are checked against each store and labelled with when. As an Amazon Associate, Deal.ai earns from qualifying purchases.

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Price facts

  • Lowest price today: $25.71 at Amazon (checked Nov 11, 2026).
  • Checked at 16 stores.

Our take on the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)

Simparica Trio is a monthly prescription-strength chew that combines flea, tick, heartworm and intestinal worm protection in one dose. The active ingredients are sarolaner, moxidectin and pyrantel pamoate, and the liver-flavored tablet is taken with or without food. It suits owners of dogs in the 11.1–22 lb range who want to replace separate flea, tick and heartworm products with a single chew. Compared with giving three products, it cuts the monthly routine to one step, though it costs more than buying a plain flea tablet alone.

Best forSmall-dog owners who want one monthly chew instead of three productsHouseholds fighting flea re-infestationDogs that take tablets readilyOwners who travel with dogs and need broad parasite cover
Pros
  • Covers fleas, six tick species, heartworm, roundworm and hookworm in one dose
  • Kills adult fleas within 4 hours and reaches full kill by 8 hours
  • Fleas die before laying eggs, which helps break the home life cycle
  • Liver-flavored chew that most dogs take voluntarily
  • Given with or without food, so no timing around meals
  • Sized by weight band, so dosing is straightforward for small breeds
Cons
  • Requires a veterinarian's prescription in most markets
  • Monthly dosing means missed months leave gaps in heartworm cover
  • Not for puppies under eight weeks or dogs below the weight band
  • Some dogs vomit or drool after taking it, and it should not be re-dosed without vet advice
  • Does not cover tapeworm, so a separate product is still needed if that risk exists

Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg) prices at every store

  • Lambert Vet SupplyNew

    In stock

    $38.90+ $7.99 shippingChecked 1 h ago
    Visit Lambert Vet Supply
  • Smartway Pet SuppliesNew

    In stockReturn policy

    $78.00Checked 1 h ago
    Visit Smartway Pet Supplies
  • Bandana RxNew

    In stock

    $134.42Free shippingChecked 1 h ago
    Visit Bandana Rx
  • PetPawsRxNew

    In stock

    $168.30Free shippingChecked 1 h ago
    Visit PetPawsRx
  • Chewy.comNew

    In stock

    $210.09Free shippingChecked 1 h ago
    Visit Chewy.com
  • Petco.comNew

    In stock

    $210.09Free shippingChecked 1 h ago
    Visit Petco.com
  • AmazonNew

    Availability unknown

    As an Amazon Associate, Deal.ai earns from qualifying purchases.

    $25.71Checked 1 h ago
    Visit Amazon
  • Jefferspet.comNew

    Availability unknown

    $40.05Checked 1 h ago
    Visit Jefferspet.com
  • HardyPawNew

    Availability unknown

    $40.05Checked 1 h ago
    Visit HardyPaw
  • FBNNew

    Availability unknown

    $200.31Checked 1 h ago
    Visit FBN
  • Allivet Pet PharmacyNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit Allivet Pet Pharmacy
  • Tractor Supply CompanyNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit Tractor Supply Company
  • Valley Vet SupplyNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit Valley Vet Supply
  • Koala HealthNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit Koala Health
  • PetMedsNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit PetMeds
  • VetRxDirect a Pet PharmacyNew

    Availability unknown

    $210.09Checked 1 h ago
    Visit VetRxDirect a Pet Pharmacy

Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg) price history

Lowest price we've seen: $25.71 on Nov 11 at Amazon. Tracked across 15 stores since Nov 11.

What reviewers say

  • 4.9 / 552 ratings

Owners rate it highly and mostly mention the convenience of one chew covering several parasites and dogs taking it without a fight. Complaints are uncommon and tend to involve stomach upset or a dog refusing the flavor.

What people mention
  • ConveniencePraisedOwners like replacing separate flea, tick and heartworm products with a single monthly chew.
  • Flea killPraisedUsers report fleas gone within hours of dosing and no re-infestation while dosing stays on schedule.
  • PalatabilityMixedMost dogs take the liver chew willingly, but some owners say their dog refuses it.
  • Stomach upsetCriticisedA minority of owners report vomiting or loose stool after a dose.
  • Tick coverPraisedOwners in tick-heavy areas say they find no attached ticks while using it monthly.

From Smartway Pet Supplies

  • One liver-flavored monthly chew covers heartworm, fleas, six tick species, Lyme disease prevention, roundworms and hookworms
  • Orange pack sized for small dogs 11.1–22 lbs (5.1–10 kg)
  • Sarolaner starts killing adult fleas within 4 hours and reaches 100% flea kill by 8 hours
  • Fleas die before laying eggs, helping stop re-infestation in the home
  • Clinically proven to help prevent infections that may cause Lyme disease
  • No vet prescription required; genuine Zoetis product in sealed packaging
Sizes
3 Chews, 6 Chews
Sizing
For dogs weighing 11.1–22 lbs (5.1–10 kg); safe for dogs and puppies from 8 weeks of age
Guarantee
Genuine branded product, sealed and in-date, sourced from licensed Australian veterinary wholesalers
Shipping
Ships from Melbourne, Australia with tracked delivery; standard shipping to the USA takes 7–14 business days; free standard shipping over a threshold; express o
Packs
3 Chews and 6 Chews packs

About the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)

Simparica Trio is a monthly liver-flavored chewable tablet for small dogs weighing 11.1 to 22 lbs (5.1 to 10 kg). One chew covers heartworm disease, fleas, six species of ticks, roundworms and hookworms. It can be given to puppies from eight weeks of age, with or without food.

The chew combines three active ingredients: sarolaner, moxidectin and pyrantel pamoate.

Dog weight
11.1–22 lbs (5.1–10 kg)
Minimum age
8 weeks
Dosing
One chew once a month
Form
Liver-flavored chewable tablet
Feeding
With or without food
Active ingredients
Sarolaner, moxidectin, pyrantel pamoate
Flea kill
Starts within 4 hours; 100% by 8 hours
Ticks
Six species
Parasites covered
Heartworm, fleas, ticks, roundworms, hookworms

Specifications

Weight range
11.1 to 22 lbsSource
Pack count
6 Chewable Tablet(s)Source
Administration
once a monthSource

Questions and answers

What parasites does Simparica Trio cover?
It covers fleas, six species of ticks, heartworm, roundworms and hookworms, and it helps prevent the infections that cause Lyme disease. It does not cover tapeworm.
How is it different from plain Simparica?
Plain Simparica covers fleas and ticks only. Trio adds moxidectin for heartworm and pyrantel pamoate for roundworms and hookworms, so it replaces a separate heartworm preventive.
Does my dog need a prescription?
In the US and Canada this is a prescription product, so a veterinarian must authorize it. Some online sellers ask for your vet's details before shipping.
How old and how heavy must my dog be?
Puppies must be at least eight weeks old, and this orange pack is for dogs weighing 11.1 to 22 lbs. Use the next size up or down for dogs outside that band.
Can I give it with food?
Yes. It can be given with or without food, and the chew is designed to be eaten voluntarily. Give it at the same time each month.
What if my dog vomits after taking it?
Do not give another dose without asking your vet. If vomiting happens within a couple of hours, your vet may advise re-dosing or switching products.
Where is the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg) cheapest?
At Amazon, for $25.71, 88% under what the other stores charge, as of our latest check.
What do buyers say about the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)?
Rated 4.9 out of 5 from 52 ratings.
Where can I buy the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)?
16 stores we checked sell it, including Lambert Vet Supply, Jefferspet.com, HardyPaw, Bandana Rx, PetPawsRx.

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Buying guides that pick the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg)

  • Best flea and tick treatments for dogs under 40 lb

Stores we've priced the Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg) at

  • Chewy.com deals and prices
  • Tractor Supply Company deals and prices

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Minimum puppy age
eight weeks oldSource
Flea kill onset
within 4 hoursSource
Flea effectiveness
100% effectiveness in 8 hoursSource
Tick types killed
six types of ticksSource
Flavor
liver-flavored chewSource
Food administration
with or without foodSource
Voluntary consumption
9 out of 10 dogsSource
Active ingredients
sarolaner, moxidectin, and pyrantel pamoateSource